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AI蛋白质设计科学家

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Onsite

AI蛋白质设计科学家

北京安必奇生物科技有限公司

AI蛋白质设计科学家

Skills

PythonAI

8 months ago

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Important information


Contract type:

Permanent

Location:

Beijing, China

Work mode:

Onsite

Published on:

12 August 2026

What they need


该职位来源于猎聘 岗位职责: 1.模型应用与优化: 熟练使用 AlphaFold、RFDiffusion、ProteinMPNN 等工具,对蛋白质进行结构预测与亲和力优化。 2.属性设计: 围绕表达效率、溶解度及低聚集性等药物属性进行理性设计与优化。 3.闭环迭代: 基于湿实验反馈(亲和力、热稳定性),持续迭代 AI 预测模型,推动高通量验证。 4.平台维护: 参与构建并维护公司内部的蛋白设计与表达预测算法平台。 任职资格: 1.学历要求: 博士(计算生物学、生物信息学、药学或相关专业) 2.技术工具: 熟悉 AlphaFold、RoseTTAFold、ESMFold、ProteinMPNN、RFDiffusion、ColabFold。 3.项目经验: 具备蛋白质结构预测或设计项目经验,具备抗体结构优化或表达优化经验者优先。 4.编程能力: 熟练使用 Python 处理生物数据。 5.良好的学习能力、逻辑思维和跨学科沟通能力。

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