Analytical Characterization Scientist

POSITION DETAILS:

Spectrix Analytical Services, LLC is seeking a highly motivated analytical scientist to support the separations and physical sciences function in Princeton, NJ. This laboratory-based role will partner closely with the lab lead to establish purity, identity, and integrity of active pharmaceutical ingredients using chromatographic and spectroscopic techniques. The position is located in Princeton NJ.

Key Responsibilities:

· Prepare daily samples and generate analytical data

· Perform the following analyses using standard BMS methods and procedures:

o Purity analysis by UPLC, including chromatography method development and optimization as a necessary part of establishing purity (e.g., column and mobile phase screening, gradient optimization, and orthogonal conditions to detect impurities)

o Chiral purity analysis by SFC including method development and optimization

o Residual solvent analysis by GC-MS/FID

o Optical rotation, UV-Vis measurements, and other spectroscopic analyses

· Analyze, interpret, and report findings in a timely and thorough manner

· Keep accurate records of all activities in BMS-approved laboratory electronic notebooks or other approved record-keeping systems

· Adapt to changing priorities, and deadlines communicated by BMS

· Contribute to general laboratory operations, including preparing mobile phases and performing first-response troubleshooting on instruments

Required Qualifications:

· B.S./M.S. in Chemistry, Analytical chemistry, Separations sciences, or related scientific discipline with 5+ years of experience or Ph.D. with demonstrable separations and physical science experience.

· Exceptional hands-on chromatography skills, with demonstrated expertise in liquid chromatography (Waters, Agilent, or Shimadzu HPLC/UPLC), including method development and optimization, data interpretation, and troubleshooting

· Hands-on experience with SFC chiral analysis, including chiral purity and %ee determination

· Strong attention to detail and good documentation practices

· Comfort with laboratory data systems and electronic data upload

· Reliable, organized, and ability to balance multiple experimental requests

· Demonstrated curiosity, willingness to learn, and adaptability

Preferred Qualifications:

· Familiarity with chromatographic analysis of complex modalities such as peptides, ADC linker-payload, and other beyond-rule-of-five (bRo5) molecules

· Experience with advanced mass spectrometry techniques such high-resolution mass spectrometry and ms/ms interpretation

· Experience with gas chromatography (GC-FID and/or GC-MS)

· Familiarity with optical rotation, UV-Vis spectroscopy, and other spectroscopic techniques

Spectrix offers flexible schedules, competitive salaries, and a committed work environment to its employees; the company provides automatic benefits of life insurance and short and long term disability insurance. Optional benefits for full time employees include health, dental, and vision insurance, college loan assistance, and an employer matched retirement savings plan. Spectrix is not a placement agency.

Spectrix is an equal-opportunity employer. We do not discriminate on the basis of race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, disability, age, or veteran status. Spectrix complies with all applicable federal, state, and local laws governing nondiscrimination in employment.

Spectrix is participating in the E-Verify program of the U.S. Department of Homeland Security (phone number: 888-897-7781, and website: www.dhs.gov/E-Verify).

**J*_**ob Types: Full-time*_

Work Remotely

• No

Pay: $35.00 - $45.00 per hour

Benefits:

• 401(k)
• 401(k) matching
• Dental insurance
• Flexible schedule
• Health insurance
• Life insurance
• Paid time off
• Retirement plan
• Tuition reimbursement
• Vision insurance

Education:

• Bachelor's (Required)

Experience:

• Method development: 3 years (Preferred)
• HPLC: 3 years (Required)
• SFC: 3 years (Required)
• LCMS: 3 years (Required)

Work Location: In person