Associate Director, Accounting

Souffle Therapeutics | Associate Director, Accounting | Job Description

Souffle Therapeutics is a biotech company focusing on the cell-type specific delivery of genetic medicines. It’s team of driven scientists is making a mark in delivery of oligonucleotides to extrahepatic tissues. We thrive in a purpose-building lab and office space in Watertown. Come and join us in our quest!

Summary

The Associate Director of Accounting will own technical accounting, financial reporting, and the monthly close process for the company, ensuring GAAP compliance, audit readiness, and strong internal controls. This role brings deep biotech-specific expertise: clinical trial accruals, CRO/CMO accounting, R&D expense recognition, and collaboration/licensing agreements, alongside hands-on responsibility for the timely and accuracy of financial operations spanning GL, treasury, AP, payroll, fixed assets, and consolidations.

The ideal candidate thrives in a fast-paced, evolving environment and brings both strong technical accounting expertise and a proactive, process-building mindset.

Key Responsibilities

Technical Accounting & Reporting

• Strong knowledge of U.S. GAAP and SEC reporting requirements
• Experience preparing and reviewing for both private and public companies:
• Monthly, quarterly, and annual financial statements
• Form 10-K and 10-Q filings
• Audit support schedules and disclosures
• Technical accounting research and documentation
• Revenue recognition
• Equity compensation accounting (stock options, RSUs, ESPPs)
• Business combination and acquisition accounting
• Internal controls over financial reporting (SOX compliance)

Biotech / Life Sciences Experience

• Understanding of & Experience completing:
• Clinical trial accruals
• CRO and CMO accounting
• R&D expense accounting
• Collaboration, licensing, and milestone agreements
• Manufacturing inventory and pre-commercial accounting

Financial Operations

• Ownership of the monthly close process
• General ledger management
• Cash management and treasury support
• Accounts payable oversight
• Payroll review and accounting
• Fixed assets and lease accounting
• Consolidation experience

Systems & Process Improvement

• ERP experience with programs such as:
• NetSuite
• Oracle Fusion Cloud ERP
• SAP S/4HANA
• Financial reporting systems and planning tools
• Process automation and scalability initiatives
• Ability to improve close timelines and reporting efficiency

Leadership & Business Partnership

• Experience managing accounting teams
• Ability to mentor senior accountants and accounting managers
• Cross-functional collaboration with FP&A, Legal, HR, Investor Relations, and Clinical Operations
• Strong project management and communication skills
• Proven ability to partner with auditors and provide Audit Committee support

Qualifications

• CPA required
• Bachelor’s degree in Accounting or Finance
• 8–12+ years of progressive accounting experience
• Big Four public accounting experience preferred
• Public company biotech and/or life sciences experience required

Education

• Bachelor’s degree in accounting, Finance, or related field
• CPA required

At Soufflé Therapeutics, we are intentional about building an equitable culture. How we treat our people is reflective of this focus. This is an onsite position in Watertown, MA with flexibility as needed for collaboration and external engagements.