Spectrix Analytical Services, LLC

Position Position Title: Associate Scientist Compound Profiling/Biochemical Assay
The Compound Profiling group in Discovery Technologies and Molecular Pharmacology at Janssen R&amp;D is seeking a highly motivated bench scientist with diverse experience in assay optimization and execution. In this role, you will be responsible for weekly delivery of screening data to project teams to support medicinal chemistry effort in optimizing small molecules in multiple hit-to-lead and lead optimization programs. Major activities include optimizing and executing a variety of biochemical and cell-based assays suitable for establishing structure activity relationships. The successful candidate will work closely with the teams in both Therapeutic Area and Discovery Technologies and Molecular Pharmacology to miniaturize and execute assays which support drug discovery effort. We seek individuals with a strong ability to meet cycle time and deliver high quality assay results while fostering an environment of collaboration, collegiality and positive communication.
Roles and Responsibilities
<ul>
<li>Conduct testing of project compounds in multiple cellular and biochemical assays in laboratory and consistently deliver high quality data within timelines to support drug discovery R&amp;D</li>
<li>Analyze and review the cellular and biochemical assays’ pharmacology data and communicate results and suggestion for follow up experiment when it is appropriate</li>
<li>Troubleshoot pharmacology experiments when necessary to ensure delivery of consistent and high-quality data</li>
<li>Maintain excellent experimental records in Janssen electronic notebook in compliance of J&amp;J standards</li>
<li>Prepare documents that accurately describe individual steps required to perform a given protocol or task and update as required, adhering to J&amp;J standards</li>
<li>Coordinate activities for multiple projects, identify problems and proactively implement solutions</li>
</ul>
Qualifications
· A minimum of B.S. degree in biological science or related field is required.
· Experience in biochemical and cell-based assay optimization and working knowledge of conventional assay formats and technologies such as HTRF, ELISA, FP, fluorescence and luminescence is desired.
· Experience with laboratory instrumentation, such as plate reader, Combi, or Tempest is desired.
· Experience with Microsoft Office Suite and GraphPad Prism is preferred.
Spectrix offers flexible schedules, competitive salaries, and a committed work environment to its employees; the company provides automatic benefits of life insurance and short and long term disability insurance. Optional benefits for full time employees include health, dental, and vision insurance, college loan assistance, and an employer matched retirement savings plan. Spectrix is not a placement agency.
Spectrix is an equal-opportunity employer. We do not discriminate on the basis of race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, disability, age, or veteran status. Spectrix complies with all applicable federal, state, and local laws governing nondiscrimination in employment.
Job Type: Full-time
Pay: $27.00 - $30.00 per hour
Benefits:
<ul>
<li>401(k)</li>
<li>401(k) matching</li>
<li>Dental insurance</li>
<li>Flexible schedule</li>
<li>Health insurance</li>
<li>Paid time off</li>
<li>Professional development assistance</li>
<li>Tuition reimbursement</li>
<li>Vision insurance</li>
</ul>
Experience:
<ul>
<li>cell based assay: 1 year (Required)</li>
<li>ELISA: 1 year (Required)</li>
</ul>
Work Location: In person

Associate Scientist, Compound Profiling Group

Associate Scientist, Compound Profiling Group

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