Associate Scientist, Pharmacology

Cartography Biosciences is seeking a highly motivated Associate Scientist to join our Pharmacology team and play a pivotal role in the in vitro development and characterization of novel T cell engagers across our pipeline. This lab focused role centers on high-throughput functional screening as well as secondary characterization assays. The ideal candidate brings experience in T cell biology, in vitro assay development and MoA studies.

Key Responsibilities

• Execute high-throughput in vitro screening assays for T cell engagers, such as in vitro cytotoxicity.
• Perform characterization assays, including flow cytometry.
• Maintain and expand primary cell culture (PBMCs, primary T cells) and cancer cell line culture.
• Design, execute, and troubleshoot assays independently as well as in collaboration with others.
• Maintain accurate, well-organized records in the electronic lab notebook (ELN) and contribute to SOP development and assay documentation.
• Analyze, visualize, and interpret experimental data (e.g., FlowJo, GraphPad Prism, Excel).
• Contribute to general lab operations, including reagent preparation, equipment maintenance, and inventory management.
• Summarize and present experimental results and progress updates at team meetings.

Qualifications

• Master's/Bachelor's degree in Biology, or a related scientific field.
• 3+ years of relevant hands-on laboratory experience in academia or industry.
• Proficiency in tissue culture, including both primary cell culture (e.g., PBMCs, primary T cells) and cancer cell line maintenance.
• Experience in T cell biology and in vitro functional assays.
• Hands-on experience with flow cytometry.
• Strong analytical skills, with the ability to independently analyze, interpret, and troubleshoot experimental data.
• Excellent organizational skills, attention to detail, and accurate record-keeping (ELN).
• Self-motivated, adaptable, and proactive in a fast-paced environment.
• Demonstrated team player with professional and positive attitude.
• Strong written and oral communication skills.
• Able to be on-site and in person 5 days a week.

Preferred

• Experience working with T cell engagers is strongly preferred.
• Familiarity with TDCC and on-cell binding assays.
• Experience with data analysis software such as FlowJo and GraphPad Prism.

Location

South San Francisco, CA — on-site, 5 days a week (Pharmacology team).