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蛋白表达与纯化高级工程师

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蛋白表达与纯化高级工程师

上海凯莱英生物技术有限公司

蛋白表达与纯化高级工程师

1 month ago

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Important information


Contract type:

Permanent

Location:

Shanghai, China

Work mode:

Onsite

Published on:

20 September 2026

What they need


该职位来源于猎聘 【岗位职责】 1. 负责早研阶段重组蛋白/抗体在哺乳动物细胞(HEK293/CHO)、大肠杆菌及昆虫细胞等系统中的表达与纯化; 2. 独立设计并优化表达/纯化方案,解决表达量低、蛋白聚集、HCP残留等关键技术问题; 3. 熟练操作AKTA层析系统,运用亲和、离子交换、分子筛等方法完成纯化,并开展纯度、浓度、内毒素等质量检测; 4.撰写实验记录与项目报告,确保数据规范可溯; 5. 配合成药性研究、偶联业务、分析检测等内部团队,按时交付高质量蛋白样品。 【任职要求】 1. 学历专业: 博士及以上学历,生物化学、分子生物学、细胞生物学、生物工程、药学等相关专业。 2. 工作经验:博士3年及以上相关早研经验(资深/负责人岗); 3.关键技术能力: 熟练掌握至少一种蛋白表达系统(哺乳动物细胞优先); 精通AKTA操作及亲和/离子交换/分子筛等纯化方法,能独立设计纯化路线; 熟悉SDS-PAGE、Western Blot、SEC-HPLC等常规蛋白检测方法。

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