Compound Management Intern

Compound Management Specialist (Part-time Internship)

Time Commitment: 1-2 days per week

Location: Boston, MA

About Proxima

Proxima is a frontier AI and data generation company discovering the next generation of proximity therapeutics by making protein interactions programmable. Our platform brings together foundation-model machine learning, a scalable data generation engine, and a partnership track record exceeding $5B in collaborations across the world’s leading biopharma and tech organizations. We’ve recently closed an oversubscribed seed round with an elite group of VCs including DCVC, NVIDIA’s NVentures, AIX, Yosemite among others.

Neo-1 is our all-atom foundation model that combines state-of-the-art structure prediction and molecular generation in a single system. Neo-1 enables rapid exploration of chemical and structural space for high value, previously intractable targets, and in particular unlocks small molecule proximity therapeutics like molecular glues with AI for the first time.

In parallel, we are developing an advanced structural interactomics platform built on proprietary XLMS technology and a lab equipped with next-generation mass spectrometry instrumentation. This platform produces proteome-scale maps of protein interactions and helps identify small molecules that modulate proximity. Together with Neo-1, it creates an integrated system capable of co-folding protein complexes while generating candidate small molecules to influence those interactions.

Proximity-based therapeutics represent one of the most promising frontiers in modern drug discovery with the potential to treat previously intractable diseases and target ‘undruggable’ proteins. We’re building the tech and the team to make that happen. Come join us!

What you'll do

• Manage daily chemical repository routines, encompassing the receipt, registration, and intake logging of novel materials into Mosaic
• Process assay-ready samples, including mass measurement, preparation of DMSO stocks, serial dilutions, microplate reformatting, and liquid handling automation configuration
• Ensure repository data accuracy through periodic audits, reconciling physical chemical assets with database records while managing cold-chain storage organization
• Uphold chemical safety protocols, regulatory guidelines, and hazardous material handling procedures while driving continuous enhancement of operational workflows

Your skills

• Currently enrolled in a Bachelor's program in chemistry, biochemistry, biology, or a related scientific discipline (junior or senior standing)
• Practical bench experience acquired via academic laboratory coursework, undergraduate research, or industry internships, including gravimetric analysis and micro-pipetting
• Meticulous documentation practices and precision in experimental record-keeping
• Proficiency in computational spreadsheets (Excel, Google Sheets), with prior exposure to laboratory information management systems (LIMS) being advantageous
• Understanding of standard laboratory safety regulations and hazardous reagent management
• Strong organizational capability, reliability in executing written experimental SOPs, and proactive judgment
• Strong communication skills and ability to operate within a dynamic environment

Desirable Qualifications

• Experience operating robotic liquid handling platforms, high-throughput microplate screening, or complex dilution series