Executive or Sr. Executive R&D

Roles and Responsibilities

• Develop new APIs through organic synthesis, method development, and optimization.
• Conduct literature reviews to stay updated on latest research trends and technologies.
• Ensure compliance with GMP guidelines during API manufacturing processes.
• Collaborate with cross-functional teams for product development, scale-up, and commercialization.
• Perform impurity analysis using techniques like NMR, DSC, etc.

Desired Candidate Profile

• MS/M.Sc(Science) degree in Chemistry or Ph.D/Doctorate in Chemical Sciences from a recognized university.
• Strong expertise in areas such as API synthesis, organic chemistry, method development/validation/transfer/methodology.
• 9-14 years of experience in Research & Development (R&D) or related field.

Key Responsibilities

1. Literature Review & Route Identification

• Perform comprehensive literature and patent searches (SciFinder, Reaxys, PubChem, etc.).
• Identify and evaluate synthetic routes for APIs, intermediates, and impurities.

2. Synthetic Research & Development

• Plan and perform multi-step organic synthesis experiments.
• Develop and optimize cost-effective and robust synthetic processes.
• Work on impurity profiling and synthesis of known/unknown impurities (including nitrosamines/nitroamines).

3. Process Optimization & Scale-Up Support

• Optimize reaction parameters for higher yield, purity, and reproducibility.
• Support process development, kilo-lab trials, and technology transfer.
• Address scale-up challenges in collaboration with process R&D teams.

4. Analytical Collaboration

• Interpret analytical data (HPLC, LC-MS, NMR, IR) for structure confirmation.
• Work with Analytical R&D to characterize intermediates, APIs, and impurities.

5. Documentation & Compliance

• Maintain accurate lab notebooks, experiment records, and reports.
• Prepare technical documents for DMFs, ANDAs, and regulatory submissions.
• Ensure GLP, GMP, EHS, and data integrity compliance.

6. Teamwork & Leadership (For Sr. Executive Level)

• Independently lead assigned projects with minimal supervision.
• Mentor and guide junior chemists/trainees in lab activities.
• Provide technical support for regulatory/customer queries.