Flow Cytometry Lab Scientist

Kelly Science and Clinical FSP is currently seeking a Flow Cytometry Scientist for a long term engagement in Spring House, PA with one of our Global clients. This person will join our Kelly FSP (Functional Service Provider) division, a managed solution provider and business unit of Kelly Services, Inc. This role is full-time and is offering full benefit options. As a Kelly FSP employee you may be eligible for Medical, Dental, Vision, 401K and a variety of other benefits to choose from. You may also be eligible for paid time off, including holiday, vacation, and sick/personal time.

Lab-based flow cytometry scientist Position Summary We are seeking a passionate and talented scientist, as a contractor, to join the Clinical Cytometry group within Biomarker Development & Operations in Spring House, PA. This role will support client Oncology clinical programs by delivering fit-for-purpose flow cytometry biomarker assays and high-quality clinical data in a highly collaborative clinical research environment.

The successful candidate will be lab-based and should have experience with flow cytometry, primary cell handling, and cell-based assays. The role will focus on designing and executing robust ex vivo flow cytometric assays with immunophenotyping and functional readouts. Hands-on experience with clinical flow cytometry assay development, optimization, analytical validation and clinical sample analysis is highly valued.

Primary Responsibilities (including, But Are Not Limited To)

• Execute multi-parameter clinical flow cytometry biomarker assays end-to-end including assay development, optimization, fit-for-purpose validation, on-time assay deployment for clinical sample testing, and downstream analysis
• Design, develop, and perform robust ex vivo and in vitro cell-based assays that incorporate functional readouts, including activation, proliferation, cytokine production, and cytotoxicity
• Handle and isolate primary human cells from blood and cryopreserved specimens for characterization and functional assessment
• Record experimental data and results accurately and well-organized following SOPs and internal document requirements including writing validation reports
• Demonstrate the ability to analyze, interpret, and present data in professional 'publication ready' format
• Demonstrate clear and professional verbal and written communication and effectively present scientific data and concepts
• Support clinical flow cytometry research projects implemented externally at external service providers/CROs.
• Monitor data quality resulting from outsourced clinical flow cytometry assays. Perform assay troubleshoot to correct errors, identify root-cause of errors and prevent re-occurrence.
• Work independently and manage multiple projects simultaneously
• Demonstrate the ability to contribute to various projects outside of his/her own, and collaborate with stakeholders from all relevant functions

Qualifications

• Education: A B.S. with 3+ years, a M.S. with 2+ years, or a PhD in biomedical sciences with 1+ year of flow cytometry laboratory experiences are required. Pharmaceutical/biotech industry experience is a plus but not necessary. Related Experience:
• Extensive hands-on experience in developing, validating, implementing and testing high-dimensional flow cytometry assays is required. The candidate should be versed in the analysis of such multi-dimensional flow cytometry experiments with the appropriate instruments (BD/Waters & Cytek preferred) and software (particularly FlowJo, OMIQ) and ability to learn new analytical software packages. Experience with FACS cell sorting is not necessary but valuable.
• Proficiency in PBMC/BMMC isolation and cryopreservation is required. Experience with primary cell culture techniques is required. Expertise in immune cell isolation from whole blood, tissues or tumor dissociation is a plus.
• Background in Oncology and/or Immunology is desirable, as well as the ability to understand and willingness to integrate current scientific literature into research practice.
• Experience with managing research projects at clinical flow cytometry specialty labs/CROs including assay development, analytical validation, and assay implementation is highly valuable Personal Skills:
• Flexibility and interest in learning/developing new techniques and skills in accordance with the research program needs
• Position requires ability to work independently and as part of a larger team. Therefore, excellent communication skills, both written and verbal, and strong interpersonal skills are necessary.

Posted By: Karli Minor