Histopathology Technologist (m/f/d) - Tissue & Spatial Technologies Platform

Overview

For the Tissue & Spatial Technologies Platform within Roche's 360 Labs Initiative, we are seeking an experienced Histopathology Technologist to support histology operations and contribute to the successful implementation and growth of an open-access research platform. The successful candidate will provide high-quality histology services, train platform users, support assay development activities, and work closely with scientists across multiple therapeutic areas to accelerate early drug discovery programs.

This position requires extensive hands-on histology expertise, strong technical problem-solving capabilities, and the ability to operate independently within a highly collaborative research environment.

Contract Details

• Start Date: 01.11.2026
• Latest Possible Start Date: 01.12.2026
• Duration: 9 months (maternity cover)
• Extension: Not anticipated
• Workload: 100%
• Location: Basel, Switzerland
• Home Office: Not available
• Travel Requirements: None
• Team Size: 13
• Working Hours: Standard business hours
• GMP Environment: No
• Criminal Record Extract Required: Yes

Responsibilities

• Perform complete histology workflows including tissue processing, embedding, microtomy, cryosectioning, staining, imaging and slide digitization.
• Execute and optimize histological staining protocols including:
• Hematoxylin & Eosin (H&E)
• Immunohistochemistry (IHC)
• In Situ Hybridization (ISH)
• Immunofluorescence (IF)
• Work with a broad range of mammalian tissues, including delicate and challenging specimen types.
• Operate, maintain, troubleshoot and perform quality control activities on histology laboratory instruments.
• Generate high-quality and reproducible data through strict adherence to laboratory procedures and assay documentation standards.
• Train and support scientists and laboratory users on histology equipment and workflows.
• Collaborate with research teams to develop and improve tissue-based assays for early drug discovery projects.
• Contribute to continuous process improvement initiatives within the platform.
• Monitor scientific developments and emerging technologies in histopathology and tissue analysis.

Mandatory Requirements

Education & Experience

• University degree in Life Sciences or completed training as a Laboratory Technologist.
• Minimum 3 years of hands-on experience in a histology laboratory environment.

Technical Expertise

Applicants must demonstrate extensive practical experience in:

• Tissue fixation
• Tissue processing
• Embedding
• Paraffin sectioning
• Cryosectioning
• Histological staining techniques
• Immunohistochemistry (IHC)
• In Situ Hybridization (ISH)
• Immunofluorescence (IF)

Additionally, candidates must have:

• Strong expertise in handling mammalian tissues.
• Experience working with delicate samples such as cryopreserved nervous-system tissues, organoids, or comparable in vitro models.
• Deep understanding of histology laboratory equipment operation, maintenance and troubleshooting.
• Knowledge of assay documentation requirements and laboratory quality standards.
• Experience with digital pathology technologies, including whole-slide scanning, is advantageous.

Personal Competencies

• High level of manual dexterity and precision when handling biological samples.
• Strong attention to detail and commitment to data quality.
• Excellent organizational and problem-solving skills.
• Customer-oriented mindset with a proactive and service-driven approach.
• Ability to work independently while collaborating effectively within multidisciplinary teams.
• Fluent English communication skills, both written and spoken.

Candidate Profile

The ideal candidate is an experienced histology specialist who combines exceptional laboratory skills with a strong service mentality. They are comfortable working in a dynamic research environment, take ownership of their responsibilities, and can support both routine laboratory operations and scientific innovation. Practical expertise in tissue preparation and staining is essential, and candidates must be able to demonstrate significant hands-on experience rather than purely administrative, quality, or coordination-focused backgrounds.