PhD Position in Single-Molecule Biophysic

PhD Position in Single-Molecule Biophysic We are seeking a motivated PhD student to use single-molecule techniques and computational tools to explore molecular interactions and apply them for therapeutic applications. Job description We are looking for a PhD student passionate about understanding molecular mechanisms in biological systems. This position involves applying single-molecule techniques to study molecular interactions, including protein-ligand interactions and protein-peptide interactions. The candidate will work in an interdisciplinary environment, combining experimental approaches (single molecule fluorescence and biochemistry) with computational methods. The candidate will obtain single-molecule multiplexing data and validate machine learning predictions using the high-throughput data. The successful candidate will collaborate with international partners for therapeutic applications of this research. The project offers opportunities to make significant contributions to understanding molecular interactions and their implications for both fundamental and medical sciences. Job requirements MSc degree (or nearing completion) in physics, biophysics, computational biology, or a related field. Strong programming skills (Python) and experience in data analysis and computational methods. Familiarity with molecular biology techniques. Excellent written and spoken English skills. Ability to work effectively in a collaborative, international, and interdisciplinary environment. This position is part of a Marie Skłodowska-Curie Doctoral Network. Applicants must satisfy the MSCA mobility rule: at the time of recruitment, they must not have lived or carried out their main activity, such as work or study, in the Netherlands for more than 12 months during the previous 36 months. The rule applies regardless of nationality. TU Delft (Delft University of Technology) Working at TU Delft means contributing to solutions that really make a difference. For over 180 years, we have been training engineers who make an impact worldwide in companies, government bodies, or as entrepreneurs. Our alumni turn knowledge into concrete solutions for the challenges of today and tomorrow. These challenges are changing rapidly. That is why we focus on themes such as energy, climate, digitalisation, artificial intelligence (AI), and smart mobility every day. Our education and research are directly aligned with what society needs now and in the future. At TU Delft, our people make the difference. With their knowledge and curiosity, our staff provide a high-quality education and conduct pioneering research that extends beyond the campus. You will have the opportunity to take the initiative, work with others, and grow as a professional. Working at TU Delft means join an international community of professionals and students. Together, we create knowledge, innovations, and solutions that help move the world forward. Faculty Applied Sciences With more than 1,100 employees, including 150 pioneering principal investigators, as well as a population of about 3,600 passionate students, the Faculty of Applied Sciences is an inspiring scientific ecosystem. Focusing on key enabling technologies, such as quantum- and nanotechnology, photonics, biotechnology, synthetic biology and materials for energy storage and conversion, our faculty aims to provide solutions to important problems of the 21st century. To that end, we educate innovative students in broad Bachelor's and specialist Master's programmes with a strong research component. Our scientists conduct ground-breaking fundamental and applied research in the fields of Life and Health Science & Technology, Nanoscience, Chemical Engineering, Radiation Science & Technology, and Engineering Physics. We are also training the next generation of high school teachers. about this vacancy please contact Chirlmin Joo, via [email protected]. Application procedure Are you interested in this vacancy? Please apply no later than 1 November 2026 upload the following documents: CV Motivational letter It is highly recommended that the candidate makes an inquiry by emailing Chirlmin Joo before submitting their application. You can address your application to Chirlmin Joo. #EUfunded This is an EU funded project, named MORPHEOS: neuroMORPHic fluidic circuits Enabled by artificial iOn channelS, with project number 101311970, within program Horizon Europe / Marie Skłodowska-Curie Actions Doctoral Networks Doing a PhD at TU Delft requires English proficiency at a certain level to ensure that the candidate is able to communicate and interact well, participate in English-taught Doctoral Education courses, and write scientific articles and a final thesis. For more details please check the Graduate Schools Admission Requirements. Please note: You can apply online. We will not process applications sent by email and/or post. As part of knowledge security, TU Delft conducts a risk assessment during the recruitment of personnel. We do this, among other things, to prevent the unwanted transfer of sensitive knowledge and technology. The assessment is based on information provided by the candidates themselves, such as their motivation letter and CV, and takes place at the final stages of the selection process. When the outcome of the assessment is negative, the candidate will be informed. The processing of personal data in the context of the risk assessment is carried out on the legal basis of the GDPR: performing a public task in the public interest. You can find more information about this assessment on our website about knowledge security. Please do not contact us for unsolicited services.

Faculty/Department: Faculty of Applied Sciences

Salary range: €3059 - €3881

Hours per week: 38

FTE: 1,0

Submission is possible until: 1 Nov 2026

ID job: 3828