Photonic microscopy engineer

Organization: BioImaging and Pathologies Laboratory

Location: 74 Route du Rhin, Illkirch-Graffenstaden, France

Send CV, Publications, Summary And References To Elisa Bombarda at [email protected]

cc: [email protected]

Position Information The BioImaging and Pathologies Laboratory (LBP) is recruiting a Research Engineer for a 12-month position within the Biophotonics of Molecular and Cellular Interactions (BIMC) team. At the interface of biophysics, biology and chemistry, BIMC develops advanced fluorescence-based approaches to study biomolecular interactions involved in infection and epigenetic regulation.

The successful candidate will implement and validate Transient-State (TRAST) spectroscopy , a fluorescence technique designed to probe fluorophore dark-state dynamics. The method will then be integrated into the PIQ-QuESt imaging platform and made available to academic and industrial users.

Main missions

• Instrumental development – Assembly and align a complete laser based set-up (laser sources, AOM, beam delivery optics, and sCMOS camera detector),
• Instrument Validation – Demonstrate performance with a benchmark chromophore that populates dark states (e.g., the photo isomerisation dynamics of the pentamethine cyanine Cy5),
• Data analysis pipeline – Implement, test and document software tools for real time acquisition and quantitative analysis of TRAST data.

Profile

Required knowledges

• Hands-on experience with photonic spectroscopy hardware (lasers, modulators, detectors),
• Solid understanding of optical alignment and beam propagation principles.
• Proficiency in at least one programming environment: MATLAB, Python, LabVIEW or Arduino,
• Familiarity with fluorescence microscopy data processing,
• Basic knowledge of (bio)molecular systems and their photophysics,
• English proficiency at B2 level (or higher).

Desired Skills And Personal Qualities

• Precision and rigor in experimental work; strong troubleshooting mindset,
• Ability to write clear user protocols and to contribute to scientific publications,
• Good visual and oral presentation skills,
• Proven team spirit and ability to collaborate effectively within a multidisciplinary group.

How to apply

The Application Should Include The Following Documents

• Curriculum Vitae (including a list of publications, if any),
• Cover letter describing your relevant experience and motivation for the position,
• Names and contact details of two academic/professional references.

Send Your Application To

• Dr. habil. Elisa Bombarda ([email protected]) –Project coordinator
• Dr. Ludovic Richert ([email protected]) – Facility head of PIQ-QuEst.

Deadline to apply: September 30, 2026 2026_Profile_IE_TRAST_PIQDownload

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