Protein Analytics Scientist

We are seeking a highly motivated Scientist with experience in protein analytics to join the Protein Science group within Discovery Biotherapeutics in Cambridge, MA. The successful candidate will play a key role in supporting biologics discovery and lead optimization efforts by characterizing protein therapeutic candidates, including highly engineered biotherapeutic formats. This position offers the opportunity to contribute directly to the advancement of innovative therapeutic programs while leveraging high-throughput technologies, automation, and modern analytical platforms.

The ideal candidate is scientifically curious, detail-oriented, and highly organized, with a strong commitment to data quality, reproducibility, and collaborative problem-solving. Experience working in electronic laboratory environments and managing analytical data is highly desirable.

Key Responsibilities

· Perform analytical characterization of proteins using a broad suite of methods, including:

o Analytical size exclusion chromatography (anSEC)

o Hydrophobic interaction chromatography (HIC)

o Reverse-phase chromatography (RP-HPLC)

o SDS-PAGE

o CE-SDS

o cIEF

o Endotoxin analysis

· Maintain and operate analytical instrumentation to support protein characterization workflows.

· Generate high-quality analytical data and contribute to comprehensive characterization packages supporting hit identification, lead selection, and candidate optimization.

· Collaborate effectively within a multidisciplinary team and communicate results clearly through data reports, presentations, and electronic data management systems.

· Contribute to continuous improvement initiatives, including method development, implementation of automation, workflow optimization, and enhanced laboratory efficiency.

Qualifications Required

· B.S. or M.S. in Biology, Biochemistry, Chemical Engineering, Bioengineering, or a related scientific discipline.

· Minimum of 1 year of relevant industry or academic laboratory experience.

· Experience with common protein analytical techniques, including:

o anSEC

o HIC

o SDS-PAGE

o CE-SDS

o cIEF

o Spectrophotometric methods

o Endotoxin testing

· Hands-on experience with Agilent HPLC systems and Agilent OpenLab CDS software for chromatographic data acquisition and analysis.

· Strong attention to detail, scientific rigor, and data integrity.

· Excellent organizational, communication, and teamwork skills.

· Demonstrated curiosity, adaptability, and persistence in solving technical challenges.

Preferred

· Experience with LIMS, electronic laboratory notebooks, and digital data management systems.

· Experience with AKTA purification systems and protein purification workflows.

· Familiarity with mammalian cell culture and sterile laboratory techniques.

· Exposure to laboratory automation platforms and automated analytical workflows.

Why Join Us?

This role offers the opportunity to work alongside a highly collaborative Discovery Biotherapeutics team focused on advancing next-generation protein therapeutics. The successful candidate will gain broad exposure to biologics discovery, analytical characterization, high-throughput technologies, and innovative therapeutic modalities while contributing directly to critical project milestones.

*Spectrix offers flexible schedules, competitive salaries, and a committed work environment to its employees; the company provides automatic benefits of life insurance and short and long term disability insurance. Optional benefits for full time employees include health, dental, and vision insurance, college loan assistance, and an employer matched retirement savings plan. Spectrix is not a placement agency.

Spectrix is an equal-opportunity employer. We do not discriminate on the basis of race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, disability, age, or veteran status. Spectrix complies with all applicable federal, state, and local laws governing nondiscrimination in employment.

Spectrix is participating in the E-Verify program of the U.S. Department of Homeland Security (phone number: 888-897-7781, and website: www.dhs.gov/E-Verify).

Job Type: Full-time

Pay: $32.00 - $38.00 per hour

Benefits:

• 401(k)
• 401(k) matching
• Dental insurance
• Employee assistance program
• Flexible spending account
• Health insurance
• Health savings account
• Life insurance
• Paid time off
• Professional development assistance
• Referral program
• Tuition reimbursement
• Vision insurance

Education:

• Bachelor's (Required)

Experience:

• Protein Analytical: 1 year (Preferred)

Ability to Commute:

• Cambridge, MA 02142 (Required)

Work Location: In person