Research Assistant I, Spaulding Lab

MDI Bio Lab is seeking a Research Assistant I to work in the laboratory of Emily Spaulding, Ph.D.

Position Description

The Spaulding laboratory uses C. elegans to uncover mechanisms and functions of nucleolar organization and understand how disrupted nucleolar organization contributes to neurodegenerative disease.

We are seeking a highly motivated and talented Research Assistant I, preferably with lab experience in C. elegans research and/or neuroscience.

The Research Assistant will use CRISPR/Cas9 genetic engineering, advanced imaging techniques, and molecular biology to study nucleolar organization and determine how its disruption contributes to cell dysfunction.

Hourly Rate: $21.00/hour

Responsibilities

• C. elegans strain maintenance; preparation of commonly used lab reagents; ordering lab equipment and supplies; maintaining and cleaning lab equipment.
• Under the direction of senior lab staff, creation of new C. elegans strains including microinjection and genotyping.
• Works with lab team to modify and refine techniques and procedures to meet research objectives and troubleshoot new protocols. Manages multiple, concurrent projects or a multi-faceted project. Conducts a systematic and objective inquiry including experimental design, data collection and analysis.
• Clearly and concisely conveys information verbally and in written form; effectively presents ideas. Presents research results and summaries; adheres to reporting requirements of research project(s).
• Helps to train and mentor students and new lab personnel.

Basic Qualifications

Knowledge of biological sciences, as would normally be acquired through a Bachelor’s degree in biological sciences or related subject with at least 2 years of directly related experience. Other means of acquiring that knowledge and experience may be evaluated on a case-by-case basis.

Special Position Requirements and/or Preferences

• C. elegans husbandry and common molecular biology techniques such as PCR, qPCR, and western blotting, Experience with CRISPR/Cas-9 genetic editing, confocal microscopy, and/or image analysis will be an advantage. Experience with microinjection and a willingness to perfect this technique would also be highly desired.
• The candidate should be diligent, able to work both independently and in a team environment, acquire new skills rapidly, and have versatility in a laboratory setting.
• Effective problem solving, interpersonal, and mentoring skills.

Training will be available for all applied techniques used in the lab.

Work Conditions

• Ability to be in the lab during standard 9–5 working day hours.
• May be required to lift, move, and transport related laboratory equipment.
• May be required to work with hazardous materials.

The MDI Biological Laboratory celebrates and fosters an inclusive work environment and encourages people of all identities, perspectives, and backgrounds to apply.

Review of applicants will continue until the position is filled.

The MDI Biological Laboratory is an Affirmative Action/Equal Opportunity Employer.

Posted: October 6, 2026