Research Associate I

The Li lab is recruiting a Research Associate to perform cell culture and molecular biology experiments to support research projects related to mRNA therapeutics and the Sponsor Research Agreement with Rhodes Therapeutics. The research projects will involve mammalian cell culture, RNA transfection, reporter assays, qPCR, ELISA, molecular cloning, preparation of in vitro transcribed RNAs and their purifications.

The Li lab works on developing platform technologies for mRNA therapeutics. We utilize a wide range of technologies including biochemistry, chemical biology, directed evolution, and high-throughput sequencing. Essential Functions

• Perform laboratory experiments and may be responsible for a single research project
• Utilize all software relevant to experiment and equipment used
• Interpret data, form conclusions and decide on next steps under the direction of the PI or designee
• Maintain accurate records, may modify protocols with the approval of the PI or designee
• Review literature, publications and grants relevant to assigned projects
• Record results according to established lab, sponsor & university protocol
• Assist with performing data analysis and/or mathematical computations
• Maintain a detailed lab notebook according to lab practice
• Present findings at lab/group meetings
• Monitor laboratory supply levels and order as noted
• Prepare and label buffers, media, solutions, etc.
• Assist with and comply with all safety regulation and infection control standards
• Train on IACUC, IRB, EHS, Radiation safety protocols
• Comply with all applicable state, federal university, and sponsor policies and agreements
• Provide support with identifying problems and challenges, propose resolutions, implement appropriate solutions
• Provide support with drafting standard operation procedures in compliance to EHS regulation specific for the lab
• Perform other duties as required

Required Qualifications

• Bachelors degree in Biological or Natural Science, or equivalent experience
• Basic understanding of lab safety and protocols
• Knowledge of Microsoft Office products
• Ability to analyze data in a quantitative and objective manner.
• Ability to work in a team environment

The University of Massachusetts Chan Medical School welcomes all qualified applicants and complies with all state and federal anti-discrimination laws.