Research Associate II - Integrative Genomics Core

Join the forefront of groundbreaking research at the Beckman Research Institute of City of Hope, where we're changing lives and making a real difference in the fight against cancer, diabetes, and other life-threatening illnesses. Our dedicated and compassionate faculty and staff are driven by a common mission: Contribute to innovative approaches in predicting, preventing, and curing diseases, shaping the future of medicine through cutting-edge research.

We are seeking a highly motivated Research Assistant II to join the Integrative Genomics Core. You will support a wide range of genomics workflows, including next-generation sequencing (NGS) library preparation, nucleic acid extraction, and quality control processes.

The Integrative Genomics Core provides comprehensive genomics services to support cutting-edge biomedical research. Leveraging advanced platforms such as Illumina, PacBio, Nanopore, and 10x Genomics, the core enables a broad range of genomic and epigenomic applications. These technologies empower investigators to explore complex biological systems, from cancer genomics to translational and precision medicine studies, within a highly collaborative, service-oriented environment.

As a successful candidate, you will:

• Perform DNA and RNA extraction, quantification, and quality control
• Prepare libraries for next-generation sequencing using Illumina, PacBio (SMRT sequencing), and 10x Genomics platforms
• Execute high-throughput workflows with attention to consistency and quality
• Track samples and metadata using laboratory information management systems FileMaker
• Maintain accurate and detailed laboratory records in accordance with core facility standards
• Assist in method development, optimization, and validation of new genomics workflows under supervision of core scientists
• Communicate effectively with core scientists regarding sample requirements, project status, and results

Your qualifications should include:

• Bachelor’s degree in molecular biology, Genetics, or related field. Master’s degree preferred.
• 2+ years of related experience in molecular biology or genomics with a Bachelor’s degree or 1+ year related experience with a Master’s degree.
• Experience with standard molecular biology techniques (PCR, qPCR, nucleic acid handling)
• 2+ years of Direct experience with next-generation sequencing library preparation is preferred
• Familiarity with Illumina sequencing platforms.
• Experience with long-read sequencing (PacBio) and/or single-cell or spatial genomics workflows (10x Genomics)

City of Hope employees pay is based on the following criteria: work experience, qualifications, and work location. City of Hope is an equal opportunity employer. To learn more about our Comprehensive Benefits, please CLICK HERE .