Research Technician

Research Technician – Neuroscience and Cancer BiologyLocation: University of Alabama at Birmingham (UAB), Birmingham, AL
Laboratory: Dr. Q. Richard Lu Laboratory
Job Type: Full-timePosition OverviewThe laboratory of Dr. Q. Richard Lu at the University of Alabama at Birmingham (UAB) is seeking a motivated and detail-oriented Research Technician to join our research team.Our laboratory investigates the molecular and cellular mechanisms underlying neurological diseases and brain cancers, with a particular focus on glial cell development, brain tumor biology, and myelin repair. Our research combines molecular biology, genetics, advanced imaging, and animal models to better understand disease mechanisms and identify potential therapeutic strategies.Major research areas include:

• Brain tumor biology: Investigating the mechanisms underlying the development, progression, and recurrence of malignant brain tumors, including glioblastoma (GBM), diffuse midline glioma (DIPG/DMG), and medulloblastoma.
• Glial cell development and myelin repair: Understanding oligodendrocyte development, myelination, and mechanisms of neurological diseases such as multiple sclerosis.
• Therapeutic development: Exploring novel targeted therapies, immunotherapies, and strategies to promote neural repair.

The successful candidate will contribute to ongoing research projects while assisting with laboratory operations, animal colony management, and experimental procedures. This position offers opportunities to develop technical expertise and participate in collaborative biomedical research.Key Responsibilities

• Assist with laboratory experiments related to neuroscience, glial biology, and brain tumor research.
• Maintain genetically engineered mouse colonies, including breeding, genotyping, and colony recordkeeping.
• Perform molecular biology techniques such as PCR, DNA/RNA extraction, and gel electrophoresis.
• Assist with tissue collection, processing, and preparation of samples for histological analysis.
• Perform immunohistochemistry, immunofluorescence staining, and microscopy.
• Assist with primary cell isolation, cell culture, and other cellular and molecular assays.
• Prepare laboratory reagents, maintain equipment, and assist with inventory management.
• Maintain accurate experimental records, organize research data, and follow established laboratory protocols.
• Work collaboratively with graduate students, postdoctoral fellows, and other research personnel.

Required Qualifications

• Bachelor's degree in Biology, Neuroscience, Molecular Biology, Biochemistry, or a related scientific discipline.
• Strong organizational skills, attention to detail, and the ability to maintain accurate records.
• Good communication and interpersonal skills.
• Ability to work both independently and as part of a research team.
• Willingness to learn new laboratory techniques and work with research animals.

Preferred Qualifications

• Previous experience in an academic or biomedical research laboratory.
• Experience with mouse handling, breeding, genotyping, or animal colony management.
• Familiarity with PCR, gel electrophoresis, and molecular biology techniques.
• Experience with tissue processing, histology, immunostaining, microscopy, or cell culture.
• Interest in neuroscience, cancer biology, developmental biology, or neurodegenerative diseases.

Previous experience with all listed techniques is not required. Training will be provided to qualified candidates who demonstrate a strong work ethic, attention to detail, and enthusiasm for scientific research.Research Environment and OpportunitiesThe Lu Laboratory provides a collaborative research environment focused on understanding the mechanisms of neurological diseases and developing innovative therapeutic approaches.The selected candidate will have opportunities to:

• Gain hands-on experience with genetically engineered mouse models and advanced experimental techniques.
• Develop research skills in molecular biology, neuroscience, and cancer biology.
• Work alongside experienced researchers on projects addressing important questions in brain tumor biology and neural repair.
• Contribute to scientific publications and presentations, depending on research involvement and contributions.
• Build a strong foundation for future careers in academic research, biotechnology, or graduate and professional education.

How to Apply

Interested candidates should submit a resume or CV and a brief cover letter outlining their relevant laboratory experience, research interests, and motivation for joining the Lu Laboratory. We welcome applicants who are enthusiastic about biomedical research, eager to learn new techniques, and interested in contributing to discoveries in neuroscience and cancer biology.

Expected hours: 40.0 per week

Work Location: In person