Scientist - III

Duties & Responsibilities

• Design, execute, and analyze cell-based experiments supporting target validation and discovery research, including routine mammalian cell culture, assay execution, image-based analysis, and iPSC-derived cell workflows.
• Operate and monitor established laboratory automation workflows for cell-based and molecular assays, troubleshoot routine issues, and escalate complex problems appropriately.
• Perform tissue, cell, and nuclei dissociation and execute NGS workflows for bulk RNA-seq, single-cell RNA-seq, single-nucleus RNA-seq, and related applications, including library preparation, quality control, quantification, normalization, sequencing setup, and sequencer operation.
• Perform routine molecular biology techniques, including DNA/RNA extraction, PCR and qPCR, nucleic acid and protein quantification, Western blotting, and basic sample preparation; analyze and interpret results, identify technical issues, and communicate findings and recommended follow-up clearly.
• Maintain accurate sample, reagent, consumable, experimental metadata, and electronic laboratory notebook records while complying with SOPs, safety requirements, company policies, and data integrity standards.
• Collaborate across cell biology, automation, genomics, and bioinformatics groups.

Skills:

• Strong hands-on experience with mammalian cell culture, cell biology, and cell-based assay execution.
• Hands-on NGS workflow experience, including tissue, cell, and/or nuclei dissociation, sequencing library preparation, quality control, and quantification for bulk RNA-seq, single-cell RNA-seq, single-nucleus RNA-seq, or related applications.
• Some hands-on experience with laboratory automation, automated instrumentation, or standardized high-throughput workflows, with the ability and interest to develop further expertise in operating and troubleshooting automated cell-based and molecular assays; automation programming is not required.
• Exceptional attention to detail and demonstrated ability to accurately execute lengthy, multi-step protocols while maintaining sample integrity, data quality, and complete documentation.
• Ability to independently troubleshoot routine experimental or operational issues, communicate clearly, and work effectively in a collaborative research environment.

Desired Skills

• Experience running laboratory automation platforms for cell-based or molecular assays.
• Experience with sequencing run setup and sequencer operation. Instrument-specific operation can be trained when required.
• Experience with human induced pluripotent stem cell culture, differentiation, characterization, or iPSC-derived cell assays.
• Experience with kidney organoid culture systems.

Education:

• Master’s degree with 3+ years of relevant experience; or
• Bachelor’s degree with 7+ years of relevant experience; or
• Equivalent combination of education and experience in cell biology, molecular biology, genomics, or a related scientific discipline.

Pay: $50.00 - $55.00 per hour

Expected hours: 40.0 per week

Work Location: In person