Senior Analyst

We are hiring!

Veeda Lifesciences is looking for Analytical Characterization specialists to join our team on-site in Bangalore. with 4 – 7 years of experience working with Biosimilars/Biologics, an in a relevant field, and hands-on expertise in HRMS, CE for biosimilars.

Responsibilities

• Execution of planned experiments/studies using physico-chemical methods.
• Develop advanced LC-MS-based methodologies (ESI, ETD, ECD) for the characterization of protein and peptide products.
• Design and implement integrated analytical strategies by combining chromatography and mass spectrometry techniques. These strategies aim to qualitatively and quantitatively assess product-related variants and impurities. This includes the development of innovative sample preparation methods, with a focus on LC-MS, CEX-MS, and SEC-MS, native MS, HDX as well as the characterization of innovator product batches sourced from various geographical regions to establish a comprehensive quality target profile.
• Lead the development of sophisticated analytical workflows, including multi-attribute methods for post-translational modifications (PTMs), sequence variant analysis, profiling of host cell proteins (HCPs), disulfide bond analysis and shuffling, cell culture metabolite analysis, and glycan profiling.
• Impurity characterization of peptides and comparability assessment with innovator using 2DLC (preferably from Agilent)
• Qualification of LCMS methods and method transfer according to ICH and regulatory guidelines.

Qualifications

• M.Sc ., MTech., or Ph.D.