CeDent
Senior Scientist
8 months ago
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Important information
Location:
Branford, CT, USA
Work mode:
Onsite
Published on:
22 August 2026
What they need
We're hiring a Senior or Principal Scientist to join our Biotherapeutics team's collaborative group focused on designing and advancing first-in-class immune-engaging biologics. If you’re a protein engineer who thrives in the lab and wants your work to move swiftly toward patients, this role offers real opportunity, purpose, and scientific challenge.
What You’ll Work On
- Design and optimize novel antibody and bispecific formats that power our next-generation immunotherapies
- Lead antibody engineering from idea to construct to bench — including expression, purification, and characterization
- Improve key attributes like affinity, stability, specificity, and PK using modern tools and data
- Drive developability assessments with platforms like SPR, BLI, DSC, DLS, ciEF, and LC-MS
- Collaborate across functional teams to support candidate selection and preclinical development
- Develop and refine functional assays for biologic characterization
- Present findings in a clear, compelling way to multidisciplinary teams
- Mentor junior scientists (if interested) and help shape our growing discovery organization
What You Bring
- PhD in Biochemistry or a related field and 5+ years of industry experience (or)
- MS with 10+ years in antibody engineering roles
- Strong foundation in antibody structure–function relationships and biologics drug development
- Expertise in protein design, expression, purification, and biophysical characterization
- Deep experience with bispecific or multispecific formats and familiarity with T cell engagers
- Working knowledge of structure–activity relationships and/or molecular modeling is a plus
- Experience with mammalian expression systems (e.g., CHO/HEK), cell-based assays, or phage/yeast display is valuable
- Strong communication, data interpretation, and cross-functional collaboration skills
Why You’ll Love Working Here
- Direct impact: Your ideas and experiments will influence platform design and help shape clinical programs
- Cutting-edge science: Work on a truly novel immunotherapy approach in a scientifically rigorous, fast-moving environment
- Personal growth: Take on visible, high-impact projects in a startup culture where contributions are recognized and development is supported
- Collaborative culture: Join a tight-knit, mission-driven team that values open communication, learning, and teamwork
- Mission with meaning: Be part of a company working to give more patients real hope in the fight against cancer
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