Sr. Clinical Research Program Manager

Affiliated Office Address

Baltimore, MD, United States

Requisition ID

122384

Date Created

September 01, 2026

Job Family

Research

Job Subfamily

General Research

Job Function

Research

Exempt Status

Exempt

Shift Type

Full Time

Schedule

M-F 8:30-5

Worksite

04-MD:School of Medicine Campus

Work Modality

Hybrid: On-site 60-89% of hours worked (Ex: 3-4 out of 5 days/week)

The Department of Neurosurgery is seeking a Sr. Clinical Research Manager who will work in collaboration with PI(s) to set the direction for research and is responsible for the overall management of a clinical trials portfolio and clinical research activities. This person plans and directs clinical research operations which typically involves external partners and internal collaborators, and/or national and international networks. The Sr. Clinical Research Manager will be responsible for managing research staff, developing and implementing effective data management and regulatory procedures, providing education to research staff, and ensuring research staff are properly trained.

Specific Duties & Responsibilities

• Collaborate with investigator(s) and exercise independent judgement in directing the conduct of the research.
• Participate in scientific discussions with collaborators, PI's, and funding organizations and contribute to decisions impacting conduct of research.
• Responsible for the recruitment, education, training, and supervision of the clinical research coordinators and regulatory personnel within the program.
• Responsible for development and implementation of policy and procedures for clinical research within the program.
• Facilitate effective teamwork among all involved personnel, e.g. research staff, research nursing, data management, regulatory personnel, hospital staff, etc.
• Ensure responsible conduct of clinical research protocols throughout the lifecycle, including development, implementation, maintenance, and termination.
• Collaborate with PIs on research protocol development and evaluation, including reviewing and assessing new protocols for clarity, thoroughness, financial and logistical feasibility, maintaining subject safety, etc.
• Oversee preparation and submissions to IRB and act as a liaison for regulatory issues on behalf of the PI.
• Track and oversee the regulatory approval process to ensure efficient study startup; assist regulatory staff with informed consent and protocol amendments for investigator-initiated studies
• Manage clinical research budget generation and financial management of the program.
• Ensure efficient use of centralized resources and adherence to policies as appropriate, e.g. clinical trial management system, prospective reimbursement analysis, etc.
• Analyze resource utilization by individual trials to ensure research needs are anticipated and met.
• Ensure adequate system for tracking and reporting clinical research milestones for financial invoicing.
• Ensure the development, testing, and evaluation of manuals, questionnaires, and coding structures for the efficient collection of data.
• Ensure research staff maintain complete and accurate research data and charts and are well prepared for auditing and monitoring visits.
• Lead study meetings to examine data, decide on next steps, implement changes to protocol operations based on results and goals, and initiate sub-studies.
• Contribute to manuscripts and presentations.
• Other duties as assigned.

Minimum Qualifications

• Bachelor's Degree in a related field.

• Six years of related experience in clinical research in an academic, government, or pharmaceutical industry environment.

• Demonstrated supervisory or lead experience.

• Additional education may substitute for required experience and additional related experience may substitute for required education permitted by the JHU equivalency formula beyond a high school diploma/graduation equivalent, to the extent permitted by the JHU equivalency formula.

Preferred Qualifications

• Master's Degree in a related field.
• Certification as a Clinical Research Professional.

Classified Title: Sr. Clinical Research Manager

Job Posting Title (Working Title): Sr. Clinical Research Program Manager (Department of Neurosurgery)

Role/Level/Range: ACRP/04/ME

Starting Salary Range: $66,215 - $116,130 Annually ($91,225 targeted; Commensurate w/exp.)

Employee group: Full Time

Schedule: M-F 8:30-5

FLSA Status: Exempt

Location: Hybrid/School of Medicine Campus

Department name: NUS Pain Institute

Personnel area: School of Medicine

Total Rewards

The referenced base salary range represents the low and high end of Johns Hopkins University’s salary range for this position. Not all candidates will be eligible for the upper end of the salary range. Exact salary will ultimately depend on multiple factors, which may include the successful candidate's geographic location, skills, work experience, market conditions, education/training and other qualifications. Johns Hopkins offers a total rewards package that supports our employees' health, life, career and retirement. More information can be found here: https://hr.jhu.edu/benefits-worklife/.

Education and Experience Equivalency

Please refer to the job description above to see which forms of equivalency are permitted for this position. If permitted, equivalencies will follow these guidelines: JHU Equivalency Formula: 30 undergraduate degree credits (semester hours) or 18 graduate degree credits may substitute for one year of experience. Additional related experience may substitute for required education on the same basis. For jobs where equivalency is permitted, up to two years of non-related college course work may be applied towards the total minimum education/experience required for the respective job.

Applicants Completing Studies

Applicants who do not meet the posted requirements but are completing their final academic semester/quarter will be considered eligible for employment and may be asked to provide additional information confirming their academic completion date.

Background Checks

The successful candidate(s) for this position will be subject to a pre-employment background check. Johns Hopkins is committed to hiring individuals with a justice-involved background, consistent with applicable policies and current practice. A prior criminal history does not automatically preclude candidates from employment at Johns Hopkins University. In accordance with applicable law, the university will review, on an individual basis, the date of a candidate's conviction, the nature of the conviction and how the conviction relates to an essential job-related qualification or function.

Diversity and Inclusion

The Johns Hopkins University values diversity, equity and inclusion and advances these through our key strategic framework, the JHU Roadmap on Diversity and Inclusion.

Equal Opportunity Employer

All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, or status as a protected veteran.

EEO is the Law

https://www.eeoc.gov/sites/default/files/2023-06/22-088\_EEOC\_KnowYourRights6.12ScreenRdr.pdf

Accommodation Information

If you are interested in applying for employment with The Johns Hopkins University and require special assistance or accommodation during any part of the pre-employment process, please contact the Talent Acquisition Office at [email protected]. For TTY users, call via Maryland Relay or dial 711. For more information about workplace accommodations or accessibility at Johns Hopkins University, please visit: https://accessibility.jhu.edu/.

Vaccine Requirements

Johns Hopkins University requires all faculty, staff, and students to receive the seasonal flu vaccine. Exceptions to the flu vaccine requirements may be provided to individuals for religious beliefs or medical reasons. Requests for an exception must be submitted to the JHU vaccination registry.

The following additional provisions may apply, depending upon campus. Your recruiter will advise accordingly.

The pre-employment physical for positions in clinical areas, laboratories, working with research subjects, or involving community contact requires documentation of immune status against Rubella (German measles), Rubeola (Measles), Mumps, Varicella (chickenpox), Hepatitis B and documentation of having received the Tdap (Tetanus, diphtheria, pertussis) vaccination. This may include documentation of having two (2) MMR vaccines; two (2) Varicella vaccines; or antibody status to these diseases from laboratory testing. Blood tests for immunities to these diseases are ordinarily included in the pre-employment physical exam except for those employees who provide results of blood tests or immunization documentation from their own health care providers. Any vaccinations required for these diseases will be given at no cost in our Occupational Health office.