Ladders
Staff Software Engineer, Variant Classification
Skills
1 month ago
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Important information
Contract type:
Permanent
Location:
United States
Work mode:
Onsite
Published on:
14 September 2026
What they need
For our client, we are seeking a Staff Software Engineer, Variant Classification to join the team of a leader in the Healthcare space.
This role will focus on building and scaling software that supports complex interpretation and classification workflows for scientific and clinical data.
The ideal candidate will partner closely with bioinformatics, laboratory, and product stakeholders to improve data translation, evidence handling, and operational efficiency.
This is an opportunity to shape reliable platforms and tools that help drive accurate results across test content and assay development initiatives.
Location: Remote - US based candidates only, no visa sponsorship available
Compensation: $100,000 – $198,000 annually
Responsibilities
- Design and build tools for accurate variant interpretation
- Develop and maintain systems for translating bioinformatic data
- Scale and optimize storage of sample-level information
- Source and maintain annotations necessary for variant interpretation
- Automate evidence placement and classification for variants
- Support test content and assay development initiatives
- Collaborate with cross-functional teams to implement solutions that meet business and technical needs
Qualifications
- Bachelor's degree and 10+ years of software development experience
- 10+ years of experience with Python at an intermediate level or higher
- 10+ years of experience with relational databases and web development frameworks
- 10+ years of experience with front-end technologies such as React, Angular, Vue.js, JavaScript, or TypeScript
- 10+ years of experience with RESTful APIs and microservices architecture
- 10+ years of experience with CI/CD pipelines and DevOps practices
- 10+ years of experience with cloud platforms such as AWS, Azure, or GCP
Benefits
- Comprehensive medical, dental, and vision insurance
- Life insurance and STD/LTD coverage
- 401(k) with employer match
- Paid Time Off (PTO) or Flexible Time Off (FTO)
- Tuition reimbursement program
- Employee stock purchase plan
Our client is an equal opportunity employer. We encourage you to apply even if you don’t meet every qualification—your background could be exactly what this team needs.
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