Karyotyping Specialist / Cytogenetics Technologist 核型分析专员/细胞遗传学技术员

该职位来源于猎聘 Job Summary/职位概述： We are seeking a highly motivated and detail-oriented Karyotyping Specialist / Cytogenetics Technologist to join our laboratory team. The successful candidate will be responsible for performing karyotype analysis, including sample preparation, culture, chromosome banding, and analysis for clinical and research applications. /我们正在寻找一位积极主动且注重细节的核型分析专员/细胞遗传学技术员加入我们的实验室团队。成功入选者将负责进行核型分析，包括样本制备、培养、染色体显带以及临床和研究应用的分析工作。 1.Key Responsibilities/主要职责：

• Perform karyotyping on various sample types (e.g., blood, bone marrow, amniotic fluid, solid tumors). /对各种样本类型（如血液、骨髓、羊水、实体瘤）进行核型分析。
• Culture and harvest cells for cytogenetic analysis./培养并收获细胞以进行细胞遗传学分析。
• Prepare and analyze G-banded chromosomes and other cytogenetic techniques./ 准备并分析 G 显带染色体及其他细胞遗传学技术。
• Interpret karyotypes and generate clinical reports. /解读核型并生成临床报告。
• Perform fluorescence in situ hybridization (FISH) when required. /在需要时进行荧光原位杂交（FISH）。
• Maintain quality control and compliance with laboratory accreditation standards. /维护质量控制并遵守实验室认证标准。
• Collaborate with pathologists, geneticists, and other laboratory staff. /与病理学家、遗传学家及其他实验室人员合作。
• Stay updated on advances in cytogenetics and contribute to process improvements./ 关注细胞遗传学的最新进展并为流程改进做出贡献。 To include in details/详细内容包括: Laboratory Operations and Management/实验室操作与管理
• Actively engage in daily laboratory management. Oversee the inventory of reagents and consumables, ensuring timely replenishment to avoid any disruptions in the testing process. This includes negotiating with suppliers for favorable terms and quality assurance. /积极参与日常实验室管理工作。监督试剂和耗材的库存情况，确保及时补充，避免检测过程出现任何中断。这包括与供应商协商以争取有利条件和质量保证。
• Be responsible for the proper maintenance and calibration of all karyotyping-related equipment. Develop a preventive maintenance schedule and troubleshoot any malfunctions promptly. For instance, work with the engineering team to repair a malfunctioning microscope imaging system to ensure uninterrupted data collection. /负责所有染色体核型分析相关设备的正确维护和校准。制定预防性维护计划，并及时排除任何故障。例如，与工程团队合作修复故障的显微镜成像系统，以确保数据收集不受干扰。
• Enforce strict laboratory safety and cleanliness standards. Train new staff members on safety protocols and ensure compliance at all times. Supervise the cleaning and sterilization of work areas and equipment to prevent cross-contamination. / 执行严格的实验室安全和清洁标准。对新员工进行安全规程培训，并确保始终遵守。监督工作区域和设备的清洁与消毒，防止交叉污染。 Procedure Documentation and Standardization/程序文件编制与标准化:
• Write, review, and update comprehensive standard operating procedures (SOPs) for all aspects of chromosome karyotyping, from sample collection to final result reporting. Ensure that these SOPs are in line with industry best practices and regulatory requirements. /编写、审查并更新染色体核型分析所有方面的全面标准操作程序（SOP），从样本采集到最终结果报告。确保这些SOP符合行业最佳实践和监管要求。
• Develop quality control procedures and checklists to monitor the consistency and reliability of test results. This includes performing regular internal audits to identify any deviations from the SOPs and taking corrective measures immediately. /制定质量控制程序和检查表，以监测测试结果的一致性和可靠性。这包括定期进行内部审计，以发现任何与标准操作程序的偏差，并立即采取纠正措施。 Collaboration and Communication/协作与沟通
• Collaborate closely with other research teams, such as genomics and molecular biology groups, to exchange knowledge and resources. Participate in joint research projects that aim to integrate karyotyping data with other genetic information for a more comprehensive understanding of genetic disorders. /与基因组学和分子生物学等其他研究团队密切合作，交流知识和资源。参与旨在将核型分析数据与其他遗传信息相结合以更全面地理解遗传疾病的联合研究项目。
• Present research findings and progress reports to both internal teams and external stakeholders. This requires excellent communication skills and the ability to translate complex scientific concepts into understandable terms for non-experts. /向内部团队和外部利益相关者展示研究结果和进展报告。这需要出色的沟通技巧，以及将复杂的科学概念转化为非专家也能理解的术语的能力。 2. Qualifications and Requirements/资格与要求: Educational Background /教育背景：
• Hold a bachelor’s degree or above in a relevant field, such as cytogenetics, molecular biology, genetics, or biotechnology. A strong foundation in cell biology and genetics is essential.

/拥有细胞遗传学、分子生物学、遗传学或生物技术等相关领域的学士学位或以上学位。具备扎实的细胞生物学和遗传学基础至关重要。

• Have completed coursework and research projects related to chromosome analysis, with a demonstrated understanding of karyotyping principles and techniques. /完成过与染色体分析相关的课程学习和研究项目，对核型分析原理和技术有深入理解。 Technical Skills/技术技能:
• Proficient in using a variety of karyotyping software and tools, such as image analysis software for chromosome counting and banding pattern recognition. Experience with advanced imaging techniques like fluorescence in situ hybridization (FISH) is highly desirable. / 熟练使用多种核型分析软件和工具，例如用于染色体计数和带型识别的图像分析软件。具备荧光原位杂交（FISH）等高级成像技术的经验者优先。
• Demonstrate excellent laboratory skills, including cell culture, chromosome harvesting, and slide preparation. Be able to perform these tasks with high precision and reproducibility. /展现出出色的实验室技能，包括细胞培养、染色体收获和玻片制备。能够以高精度和可重复性完成这些任务。 Analytical and Problem-Solving Abilities/分析和解决问题的能力:
• Possess strong analytical skills to interpret complex karyotype data and identify chromosomal abnormalities. Can correlate these findings with clinical symptoms to provide meaningful insights for diagnosis and treatment. /具备强大的分析能力，能够解读复杂的核型数据并识别染色体异常。能够将这些发现与临床症状相关联，为诊断和治疗提供有意义的见解。
• Be an effective problem-solver. When faced with technical issues in the laboratory or unexpected results, be able to quickly diagnose the problem, develop a plan of action, and implement solutions. /高效的问题解决者。当在实验室遇到技术问题或出现意外结果时，能够迅速诊断问题，制定行动计划并实施解决方案。 Communication and Teamwork/沟通与团队合作:
• Have excellent written and oral communication skills in English. Be able to write scientific reports, research papers, and communicate with international colleagues. /具备出色的英语书面和口头沟通能力。能够撰写科学报告、研究论文，并与国际同事进行交流。
• Be a team player, able to work effectively in a multidisciplinary team environment. Collaborate with colleagues from different backgrounds to achieve common research goals. /具有团队合作精神，能够在多学科团队环境中有效工作。与来自不同背景的同事合作，以实现共同的研究目标。 Research Experience/研究经验
• Have at least 2 - 3 years of relevant research experience in a laboratory setting. This could include working on research projects related to genetic disorders, cancer cytogenetics, or reproductive genetics. /具有至少 2 - 3 年的实验室相关研究经验。包括从事与遗传疾病、癌症细胞遗传学或生殖遗传学相关的研究项目。
• Proven track record of contributing to scientific publications or presentations at conferences is a plus. /有在科学出版物上发表作品或在学术会议上做报告经验者优先。