Alicja K

Applied scientific expertise to support the development of innovative therapeutic agents, guiding projects from early-stage concept through regulatory submission. Provided strategic input on scientific and regulatory aspects across nonclinical and CMC domains. • Managing and monitoring outsourced CMC activities, ensuring timely delivery and compliance with quality standards • Designing and supporting customized CMC development plans aligned with regulatory requirements • Consulting on formulation development and optimization to enhance product quality and manufacturability • Analyzing laboratory and manufacturing data to guide formulation improvements and ensure process consistency • Preparing and authoring CMC sections of regulatory submissions, including clinical trial applications and study reports • Collaborating cross-functionally with R&D, quality, and manufacturing teams to troubleshoot technical challenges and implement solutions

• Project management of multiple activities • Active participation in all daily plans of the team (French speaking environment) • Writing documents in both English and French (offers, contracts, presentations)

• Research focused on formulation and optimization of microbubbles and nanodroplets to improve drug delivery across the blood-brain barrier using ultrasound • Polymer synthesis, physicochemical characterization of emulsions • Characterization techniques: NMR, DLS, Zeta Potential, SEC, TEM, Light Microscopy, Light Microscopy, ultrasonic characterization • Thesis on ‘Fluorinated polymers for stabilization of microbubbles and nanodroplets as ultrasound agents for brain ultrasound therapy’ • Collaboration between Institut Galien (UMR CNRS 8612, the faculty of pharmacy at Université Paris Saclay) and BIOMAPS Laboratory CEA Supervisors: Nicolas Tsapis, Laurence Moine, Anthony Novell

• Assistant in research group Surfactants, Colloids and Soft Nanomaterials • Conducted research on the formulation and optimization of novel catanionic self-assembled systems using serine-modified surfactants, focusing on their potential as encapsulation nanocarriers for targeted delivery. • Developed and characterized soft matter systems with relevance to emulsions, delivery vehicles, and stabilization strategies. • Characterization by: DLS, DSC, surface tension measurement, pH measurement, Zeta Potential, phase assignment by polarized light microscopy, samples preparation, filtration extrusion

• Centre for Science and Research • Conducted in vivo studies to assess the efficacy of cosmetic ingredients within specific formulations, focusing on measurable improvements in skin properties. • Independently operated biomedical equipment including VISIA imaging, ultrasound devices, pH meters, hydration sensors, elasticity probes, and topography tools for instrumental skin analysis and objective evaluation of formulation effects. • Participated in the evaluation of cosmetic products through structured user testing, including designing consumer surveys, collecting feedback, and analyzing results to support claims related to sensory performance and user satisfaction.

• Preparation of the Bachelor thesis on Lithium-ion batteries • Experience in the battery assembly and testing • Working in a glove box, handling Swagelok type cells, chronopotentiometry, cyclic voltammetry • Retrieving data from numbers of international scientific paper readings Supervisor: Dr Dominika Buchberger